Ming-Min Shi MD, Xun-Zi Cai MD, Tiao Lin MD, Wei Wang MD, Shi-Gui Yan MD Is There Really No Benefit of Vertebroplasty for Osteoporotic Vertebral Fractures? A Meta-analysis Background Osteoporotic vertebral compressed fractures (VCFs) are the most common osteoporotic fractures. Although
The Effect of Long-term Alendronate Treatment on Cortical Thickness of the Proximal Femur
Aasis Unnanuntana MD, Kashif Ashfaq MD, Quang V. Ton MD, John P. Kleimeyer BA, Joseph M. Lane MD The Effect of Long-term Alendronate Treatment on Cortical Thickness of the Proximal Femur Background One of the radiographic hallmarks in patients with atypical
A Fracture Does Not Adversely Affect Bone Mineral Density Responses after Teriparatide Treatment
Aasis Unnanuntana MD, Quang V. Ton MD, John P. Kleimeyer BA, Joseph T. Nguyen MPH, Joseph M. Lane MD A Fracture Does Not Adversely Affect Bone Mineral Density Responses after Teriparatide Treatment Background Fracture leads to local and systemic
Rosiglitazone inhibits bone regeneration and causes significant accumulation of fat at sites of new bone formation.
Liu L, Aronson J, Huang S, Lu Y, Czernik P, Rahman S, Kolli V, Suva LJ, Lecka-Czernik B. Arkansas Children’s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Thiazolidinediones (TZDs), peroxisome proliferator-activated receptor gamma
Muscle strength and body composition are clinical indicators of osteoporosis.
Rikkonen T, Sirola J, Salovaara K, Tuppurainen M, Jurvelin JS, Honkanen R, Kröger H. Bone and Cartilage Research Unit, Mediteknia Building, University of Eastern Finland, Kuopio, Finland, toni.rikkonen@uef.fi. We examined the role of muscle strength, lean tissue distribution, and
Impaired bone health in inflammatory bowel disease: a case-control study in 80 pediatric patients.
Laakso S, Valta H, Verkasalo M, Toiviainen-Salo S, Viljakainen H, Mäkitie O. Children’s Hospital, Helsinki University Central Hospital and University of Helsinki, P.O. Box 281, 00029, Helsinki, Finland, saila.laakso@helsinki.fi. Previous studies have indicated that children with inflammatory bowel disease
Risk of nonvertebral fractures among elderly postmenopausal women using antidepressants.
Rabenda V, Bruyère O, Reginster JY. OBJECTIVE: To examine the association between antidepressants, including TCAs, SSRIs, and miscellaneous antidepressants and the risk of nonvertebral fractures among women with osteoporosis. MATERIALS AND METHODS: This study was a post-hoc analysis of
Evaluation of urinary N-telopeptide of type I collagen measurements in the management of osteoporosis in clinical practice.
Baxter I, Rogers A, Eastell R, Peel N. NIHR Musculoskeletal Biomedical Research Unit, Department of Human Metabolism, University of Sheffield, Sheffield, UK. We measured urinary N-telopeptide of type I collagen (U-NTX) to monitor response to bisphosphonates for osteoporosis. Decrease
Severity of aortic calcification is positively associated with vertebral fracture in older men-a densitometry study in the STRAMBO cohort.
Szulc P, Samelson EJ, Sornay-Rendu E, Chapurlat R, Kiel DP. INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, Lyon, France, pawel.szulc@inserm.fr. In older men, severe abdominal aortic calcification and vertebral fracture (both assessed using dual-energy X-ray absorptiometry)
Quantitative ultrasound and fracture risk prediction in non-osteoporotic men and women as defined by WHO criteria.
Chan MY, Nguyen ND, Center JR, Eisman JA, Nguyen TV. Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW, 2010, Australia. This study sought to determine the association between calcaneal quantitative ultrasound (QUS)
The effect of proton pump inhibitors on fracture risk: report from the Canadian Multicenter Osteoporosis Study.
Fraser LA, Leslie WD, Targownik LE, Papaioannou A, Adachi JD; CaMos Research Group. Department of Medicine, University of Western Ontario, London, ON, Canada, LisaAnn.Fraser@sjhc.london.on.ca. A large Canadian cohort was studied over 10 years to see if proton pump inhibitor
Cold-activated brown adipose tissue is an independent predictor of higher bone mineral density in women.
Lee P, Brychta RJ, Collins MT, Linderman J, Smith S, Herscovitch P, Millo C, Chen KY, Celi FS. Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bldg 10, CRC, 10
Adherence with bisphosphonate therapy and change in bone mineral density among women with osteoporosis or osteopenia in clinical practice.
Weycker D, Lamerato L, Schooley S, Macarios D, Siu Woodworth T, Yurgin N, Oster G. Policy Analysis Inc. (PAI), Four Davis Court, Brookline, MA, 02445, USA, dweycker@pai2.com. In clinical practice, adherence with bisphosphonate therapy varies greatly among women with
The burden of illness of osteoporosis in Canadian men.
Tarride JE, Guo N, Hopkins R, Leslie WD, Morin S, Adachi JD, Papaioannou A, Bessette L, Brown JP, Goeree R. Programs for Assessment of Technology in Health (PATH) Research Institute, St Joseph’s Healthcare, Hamilton, Ontario, Canada; Department of Clinical Epidemiology
Changes in bone biomarker concentrations and musculoskeletal symptoms among breast cancer patients initiating aromatase inhibitor therapy and women without a history of cancer.
Gallicchio L, Macdonald R, Wood B, Rushovich E, Fedarko NS, Helzlsouer KJ. The Prevention and Research Center; The Weinberg Center for Women’s Health and Medicine, Mercy Medical Center, Baltimore, MD, USA. lgallic@mdmercy.com. The objectives of this study were to
Habitual levels of high, but not moderate or low, impact activity are positively related to hip BMD and geometry: Results from a population-based study ofadolescents.
Deere K, Sayers A, Rittweger J, Tobias JH. Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK. Whether a certain level of impact needs to be exceeded for physical activity (PA) to benefit bone accrual is