Rosiglitazone inhibits bone regeneration and causes significant accumulation of fat at sites of new bone formation.

Liu L, Aronson J, Huang S, Lu Y, Czernik P, Rahman S, Kolli V, Suva LJ, Lecka-Czernik B. Arkansas Children’s Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.   Thiazolidinediones (TZDs), peroxisome proliferator-activated receptor gamma

Impaired bone health in inflammatory bowel disease: a case-control study in 80 pediatric patients.

Laakso S, Valta H, Verkasalo M, Toiviainen-Salo S, Viljakainen H, Mäkitie O. Children’s Hospital, Helsinki University Central Hospital and University of Helsinki, P.O. Box 281, 00029, Helsinki, Finland, saila.laakso@helsinki.fi.   Previous studies have indicated that children with inflammatory bowel disease

Evaluation of urinary N-telopeptide of type I collagen measurements in the management of osteoporosis in clinical practice.

Baxter I, Rogers A, Eastell R, Peel N. NIHR Musculoskeletal Biomedical Research Unit, Department of Human Metabolism, University of Sheffield, Sheffield, UK.   We measured urinary N-telopeptide of type I collagen (U-NTX) to monitor response to bisphosphonates for osteoporosis. Decrease

Severity of aortic calcification is positively associated with vertebral fracture in older men-a densitometry study in the STRAMBO cohort.

Szulc P, Samelson EJ, Sornay-Rendu E, Chapurlat R, Kiel DP. INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, Lyon, France, pawel.szulc@inserm.fr.   In older men, severe abdominal aortic calcification and vertebral fracture (both assessed using dual-energy X-ray absorptiometry)

Quantitative ultrasound and fracture risk prediction in non-osteoporotic men and women as defined by WHO criteria.

Chan MY, Nguyen ND, Center JR, Eisman JA, Nguyen TV. Osteoporosis and Bone Biology Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, NSW, 2010, Australia.   This study sought to determine the association between calcaneal quantitative ultrasound (QUS)

Adherence with bisphosphonate therapy and change in bone mineral density among women with osteoporosis or osteopenia in clinical practice.

Weycker D, Lamerato L, Schooley S, Macarios D, Siu Woodworth T, Yurgin N, Oster G. Policy Analysis Inc. (PAI), Four Davis Court, Brookline, MA, 02445, USA, dweycker@pai2.com.   In clinical practice, adherence with bisphosphonate therapy varies greatly among women with

Changes in bone biomarker concentrations and musculoskeletal symptoms among breast cancer patients initiating aromatase inhibitor therapy and women without a history of cancer.

Gallicchio L, Macdonald R, Wood B, Rushovich E, Fedarko NS, Helzlsouer KJ. The Prevention and Research Center; The Weinberg Center for Women’s Health and Medicine, Mercy Medical Center, Baltimore, MD, USA. lgallic@mdmercy.com.   The objectives of this study were to

Habitual levels of high, but not moderate or low, impact activity are positively related to hip BMD and geometry: Results from a population-based study ofadolescents.

Deere K, Sayers A, Rittweger J, Tobias JH. Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UK.   Whether a certain level of impact needs to be exceeded for physical activity (PA) to benefit bone accrual is